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Search Results for " type 2 diabetes "

20

Compounds

Cat No. Product Name Synonyms Targets
T13867 RH01386 Others
RH01386 is a small molecule that can prevent ER stress-induced β cell dysfunction and death, and inhibits proapoptotic gene expression,has the potential for type 2 diabetes treatment. RH01386 restores ER stress-impaired ...
T7544 Fucoidan Others
Fucoidan is found in various species of brown seaweed and algae,with anticancer, antiviral, neuroprotective, immune-modulating.
T2210 Genipin (+)-Genipin Others , Autophagy
Genipin ((+)-Genipin), an active aglycone derived from an iridoid glycoside called geniposide, is found in the fruit of Gardenia jasminoides Ellis.
T9022 AZD9977 AZD 9977 Glucocorticoid Receptor
AZD9977 is a novel, selective modulator of mineralocorticoid receptor .
T15159 Dorzagliatin HMS5552 Glucokinase
Dorzagliatin (HMS5552) is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell function in type 2 diabetes.
T14315 AR-9281 APAU Epoxide Hydrolase
AR-9281 (APAU) is a potent and selective inhibitor of soluble epoxide hydrolase (s-EH) potentially for the treatment of hypertension and type 2 diabetes
T3978 Linerixibat GSK2330672,Iinerixibat HBV
Linerixibat (GSK2330672) is a highly effective, nonabsorbable ASBT inhibitor (IC50: 42 ± 3 nM). It can lower glucose in an animal model of type 2 diabetes and shows excellent developability properties.
TN1418 Azaleatin DPP-4
Azaleatin is a natural product from Rhododendron simsii. Azaleatin is a dipeptidyl peptidase-IV inhibitor. Azaleatin can be used for type-2 diabetes and obesity studies.
T16074 Mifobate SR-202 PPAR
Mifobate (SR-202) is a potent and specific antagonist of PPARγ. Mifobate shows antiobesity, antidiabetic and antiatherosclerotic effects[1].
T1088 Repaglinide AG-EE 388 ZW,AG-EE 623ZW Potassium Channel , PPAR
Repaglinide (AG-EE 623ZW) is a benzoic acid derivative that stimulates insulin secretion from the pancreas and is used in the therapy of type 2 diabetes. Repaglinide has been linked to rare instances of clinically appare...
T0314 Hexylresorcinol 4-Hexylresorcinol Apoptosis , Tyrosinase , Antibacterial , Parasite
Hexylresorcinol (4-Hexylresorcinol) is a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections.
T1603 Glipizide CP 28720,K 4024 Potassium Channel , PPAR , ABC
Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity.
T22276 Bis(maltolato)oxovanadium(IV) BMOV,Bis maltolato oxovanadium,Bis(maltolato)oxovanadium (IV),bis maltolato oxo vanadium,Bis(maltolato)oxovanadium (IV) Phosphatase , Others
Bis(maltolato)oxovanadium(IV) (BMOV) is a potent, reversible, competitive and orally active pan-PTP (protein tyrosine phosphatases)inhibitor with insulin-mimicking effects and anti-diabetic properties. BMOV is a potent i...
T2385 Ipragliflozin ASP1941 SGLT
Ipragliflozin (ASP1941) is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.
T26656 ARH-049020 X334,X-334,X 334,ARH 049020
ARH-049020, a peroxisome proliferator-activated receptor (PPAR) agonist, is used potentially for the treatment of insulin resistance and type 2 diabetes.
T28182 NNC 92-1687 NNC92-1687,NNC-92-1687 Glucagon Receptor
NNC 92-1687 is a selective glucagon receptor antagonist that can be used to study type 2 diabetes.
T29019 TS-021 TS021,TS 021,TS-021 Free DPP-4
TS-021 is a selective dipeptidyl peptidase 4 (DPP-4) inhibitor with antidiabetic activity for the study of type 2 diabetes.
T3104 Globalagliatin LY2608204 Glucokinase
Globalagliatin (LY2608204) has been used in trials studying the treatment of Diabetes Mellitus, Type 2.
T15440 GSK376501A PPAR
GSK376501A is a selective and effective modulator of peroxisome proliferator-activated receptor γ (PPARγ) for the study of type 2 diabetes.
T30142 ARRY-403 AMG-151,ARRY 403,ARRY403,ARRY-403,AMG151,AMG 151 Glucokinase
ARRY-403 is a novel glucokinase activator that reduces fasting and postprandial blood glucose in patients with type 2 diabetes.
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TargetMol