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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T13867 | RH01386 | Others | |
RH01386 is a small molecule that can prevent ER stress-induced β cell dysfunction and death, and inhibits proapoptotic gene expression,has the potential for type 2 diabetes treatment. RH01386 restores ER stress-impaired ... | |||
T7544 | Fucoidan | Others | |
Fucoidan is found in various species of brown seaweed and algae,with anticancer, antiviral, neuroprotective, immune-modulating. | |||
T2210 | Genipin | (+)-Genipin | Others , Autophagy |
Genipin ((+)-Genipin), an active aglycone derived from an iridoid glycoside called geniposide, is found in the fruit of Gardenia jasminoides Ellis. | |||
T9022 | AZD9977 | AZD 9977 | Glucocorticoid Receptor |
AZD9977 is a novel, selective modulator of mineralocorticoid receptor . | |||
T15159 | Dorzagliatin | HMS5552 | Glucokinase |
Dorzagliatin (HMS5552) is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell function in type 2 diabetes. | |||
T14315 | AR-9281 | APAU | Epoxide Hydrolase |
AR-9281 (APAU) is a potent and selective inhibitor of soluble epoxide hydrolase (s-EH) potentially for the treatment of hypertension and type 2 diabetes | |||
T3978 | Linerixibat | GSK2330672,Iinerixibat | HBV |
Linerixibat (GSK2330672) is a highly effective, nonabsorbable ASBT inhibitor (IC50: 42 ± 3 nM). It can lower glucose in an animal model of type 2 diabetes and shows excellent developability properties. | |||
TN1418 | Azaleatin | DPP-4 | |
Azaleatin is a natural product from Rhododendron simsii. Azaleatin is a dipeptidyl peptidase-IV inhibitor. Azaleatin can be used for type-2 diabetes and obesity studies. | |||
T16074 | Mifobate | SR-202 | PPAR |
Mifobate (SR-202) is a potent and specific antagonist of PPARγ. Mifobate shows antiobesity, antidiabetic and antiatherosclerotic effects[1]. | |||
T1088 | Repaglinide | AG-EE 388 ZW,AG-EE 623ZW | Potassium Channel , PPAR |
Repaglinide (AG-EE 623ZW) is a benzoic acid derivative that stimulates insulin secretion from the pancreas and is used in the therapy of type 2 diabetes. Repaglinide has been linked to rare instances of clinically appare... | |||
T0314 | Hexylresorcinol | 4-Hexylresorcinol | Apoptosis , Tyrosinase , Antibacterial , Parasite |
Hexylresorcinol (4-Hexylresorcinol) is a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections. | |||
T1603 | Glipizide | CP 28720,K 4024 | Potassium Channel , PPAR , ABC |
Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity. | |||
T22276 | Bis(maltolato)oxovanadium(IV) | BMOV,Bis maltolato oxovanadium,Bis(maltolato)oxovanadium (IV),bis maltolato oxo vanadium,Bis(maltolato)oxovanadium (IV) | Phosphatase , Others |
Bis(maltolato)oxovanadium(IV) (BMOV) is a potent, reversible, competitive and orally active pan-PTP (protein tyrosine phosphatases)inhibitor with insulin-mimicking effects and anti-diabetic properties. BMOV is a potent i... | |||
T2385 | Ipragliflozin | ASP1941 | SGLT |
Ipragliflozin (ASP1941) is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2. | |||
T26656 | ARH-049020 | X334,X-334,X 334,ARH 049020 | |
ARH-049020, a peroxisome proliferator-activated receptor (PPAR) agonist, is used potentially for the treatment of insulin resistance and type 2 diabetes. | |||
T28182 | NNC 92-1687 | NNC92-1687,NNC-92-1687 | Glucagon Receptor |
NNC 92-1687 is a selective glucagon receptor antagonist that can be used to study type 2 diabetes. | |||
T29019 | TS-021 | TS021,TS 021,TS-021 Free | DPP-4 |
TS-021 is a selective dipeptidyl peptidase 4 (DPP-4) inhibitor with antidiabetic activity for the study of type 2 diabetes. | |||
T3104 | Globalagliatin | LY2608204 | Glucokinase |
Globalagliatin (LY2608204) has been used in trials studying the treatment of Diabetes Mellitus, Type 2. | |||
T15440 | GSK376501A | PPAR | |
GSK376501A is a selective and effective modulator of peroxisome proliferator-activated receptor γ (PPARγ) for the study of type 2 diabetes. | |||
T30142 | ARRY-403 | AMG-151,ARRY 403,ARRY403,ARRY-403,AMG151,AMG 151 | Glucokinase |
ARRY-403 is a novel glucokinase activator that reduces fasting and postprandial blood glucose in patients with type 2 diabetes. |